What should the talk be about?
TypeORM, ORMs in general.
Why is that important?
ORMs are super popular in Node.js community. Moreover, TypeORM is sometimes used as an example of a big project elegantly put together with TypeScript. Although they get some bad rep, ORMs are still the way to go for many.

https://www.silasreinagel.com/blog/2018/11/12/using-orms-and-dtos-elegantly/
Who will learn from it?
People using TypeScript with Node.js.
What should the talk be about?
TypeORM, ORMs in general.
Why is that important?
ORMs are super popular in Node.js community. Moreover, TypeORM is sometimes used as an example of a big project elegantly put together with TypeScript. Although they get some bad rep, ORMs are still the way to go for many.
https://www.silasreinagel.com/blog/2018/11/12/using-orms-and-dtos-elegantly/
Who will learn from it?
People using TypeScript with Node.js.